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How an exercise-activated enzyme helps to keep the brain young
- RESEARCH HIGHLIGHT
- 25 February 2026
How an exercise-activated enzyme helps to keep the brain young
A protein reinforces the blood–brain barrier, which becomes leaky with age.
[Microscopy image of a section of human liver, shown in various shades of light and dark purple]
An enzyme produced by liver cells (pictured) has anti-ageing effects on the brain. Credit: Biophoto Associates/Science Photo Library
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Exercise prevents brain ageing and memory loss by strengthening the blood–brain barrier, the structure that keeps harmful substances out of the brain1.
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doi: https://doi.org/10.1038/d41586-026-00515-x
References
Bieri, G. et al. Cell https://doi.org/10.1016/j.cell.2026.01.024 (2026).
Subjects
Physiology
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