During the proof stage of this paper, the description of the statistical method in the legend for Fig. 4e was incorrectly edited to “Two-sided Fisher’s exact test, p value reported on graph.” The correct statistical method used, as stated during the peer review process, was a directional score test for equality of proportions using a Chi-square approximation. We have now corrected this in the figure legend to state “One-sided Chi-squared analysis, p value reported on graph.” We also note that the p value for comparison of WT to Tg animals is 0.036, not 0.032 as originally presented in the figure. The conclusions of this panel are unchanged.

For Extended Data Fig. 9d, we note that the statistical tests performed and significance values of presented comparisons are shown correctly. To prevent confusion in interpreting our calculations, we have amended Extended Data Fig. 9d to include the results of Hmgn+/– genotype and the associated p value in comparison to WT animals (ns). The figure legend now includes total animals measured (n = 267) and significance value of WT and Hmgn+/– comparison (p = 0.8168).

The Methods sections “MicroCT” and “Postnatal survival assay” have also been corrected to reflect these changes. All changes are included in the HTML and PDF versions of this article.

Author information

Sanjeev S. Ranade

Present address: Center for Cardiovascular and Muscular Diseases, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA

Sanjeev S. Ranade

Present address: Center for Data Science and Artificial Intelligence, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA

These authors contributed equally: Sanjeev S. Ranade, Feiya Li

Authors and Affiliations

Gladstone Institutes, San Francisco, CA, USA

Sanjeev S. Ranade, Feiya Li, Sean Whalen, Angelo Pelonero, Lin Ye, Yu Huang, Abigail Brand, Tomohiro Nishino, Rahul Mital, Frances Koback, Arun Padmanabhan, Victoria Yu, Alexander F. Merriman, Langley Grace Wallace, Annie Nguyen, Nikolaos Poulis, Mauro W. Costa, Casey A. Gifford, Katherine S. Pollard & Deepak Srivastava

Roddenberry Center for Stem Cell Biology and Medicine at Gladstone, San Francisco, CA, USA

Sanjeev S. Ranade, Feiya Li, Angelo Pelonero, Lin Ye, Yu Huang, Abigail Brand, Tomohiro Nishino, Rahul Mital, Frances Koback, Arun Padmanabhan, Victoria Yu, Alexander F. Merriman, Langley Grace Wallace, Annie Nguyen, Nikolaos Poulis, Mauro W. Costa, Casey A. Gifford & Deepak Srivastava

Department of Biomedical Engineering, Duke University, Durham, NC, USA

Ryan M. Boileau

Center for Advanced Genomic Technologies, Duke University, Durham, NC, USA

Ryan M. Boileau

Division of Cardiology, Department of Medicine, University of California, San Francisco, San Francisco, USA

Arun Padmanabhan

Cardiovascular Research Institute, University of California, San Francisco, San Francisco, USA

Arun Padmanabhan

Center for Cardiovascular and Muscular Diseases, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA

Bastien Cimarosti & Diana Presas-Ramos

Center for Data Science and Artificial Intelligence, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA

Bastien Cimarosti & Diana Presas-Ramos

Department of Pediatrics, Stanford University School of Medicine, Stanford, CA, USA

Casey A. Gifford

Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA

Casey A. Gifford

Chan Zuckerberg Biohub, San Francisco, CA, USA

Katherine S. Pollard

Department of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA, USA

Katherine S. Pollard

Bakar Computational Health Sciences Institute, University of California, San Francisco, San Francisco, CA, USA

Katherine S. Pollard

Institute for Human Genetics, University of California, San Francisco, San Francisco, CA, USA

Katherine S. Pollard

Department of Pediatrics, University of California, San Francisco, San Francisco, CA, USA

Deepak Srivastava

Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, CA, USA

Deepak Srivastava

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Sanjeev S. Ranade

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Feiya Li

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Sean Whalen

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Angelo Pelonero

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Lin Ye

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Yu Huang

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